CLINICAL OBSERVATION OF A LOW-AGGRESSIVE COURSE OF ADRENOCORTICAL CANCER

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Published: 2022-12-06
Keywords:
adrenal glands, adrenocortical cancer, indolent course, clinic, treatment

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Наталья Николаевна Константинова
Kuzbass Clinical Hospital named after S.V. Belyaev, Kemerovo
Валерия Викторовна Романова
Kuzbass Clinical Pathology and Anatomical Bureau, Kemerovo
Александр Карлович Лейсле
Kuzbass Clinical Hospital named after S.V. Belyaev, Kemerovo
http://orcid.org/0000-0001-8087-2076 (unauthenticated)
Светлана Ивановна Елгина
Kemerovo State Medical University
Вадим Гельевич Мозес
Kemerovo State University image/svg+xml
Елена Владимировна Рудаева
Kemerovo State Medical University
Кира Борисовна Мозес
Kemerovo State Medical University

Abstract

Adrenocortical cancer (ACR) is a rare malignant tumor characterized by an aggressive clinical course with a high mortality rate and an unfavorable therapeutic prognosis. However, in some cases, ACR proceeds indolently, when patients with proven distant metastases or recurrence of ACR live without progression for a sufficiently long time. A clinical case of a patient whose primary tumor was diagnosed and removed 13 years ago (in 2009) is presented. Subsequently, she underwent the removal of recurrent and metastatic tumors three times (in 2011, in 2015 and in 2018). Currently, according to PET CT with 18F-FDG, nodular formations with low metabolic activity are determined in the subdiaphragmatic space of the patient.

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Article Details

Issue

Vol. 21 No. 4 (2022): December

Section

CASE HISTORY

Author Biographies

Наталья Николаевна Константинова, Kuzbass Clinical Hospital named after S.V. Belyaev, Kemerovo

candidate of medical sciences, surgeon, endocrinologist, department of endocrine surgery

Валерия Викторовна Романова, Kuzbass Clinical Pathology and Anatomical Bureau, Kemerovo

pathologist

Александр Карлович Лейсле, Kuzbass Clinical Hospital named after S.V. Belyaev, Kemerovo

radiologist, radiology department N 2

Светлана Ивановна Елгина, Kemerovo State Medical University

doctor of medical sciences, docent, professor of department of obstetrics and gynecology N 1

Вадим Гельевич Мозес, Kemerovo State University

doctor of medical sciences, professor, director of the Medical Institute

Елена Владимировна Рудаева, Kemerovo State Medical University

candidate of medical sciences, docent, docent of the department of obstetrics and gynecology named after G.A. Ushakova

Кира Борисовна Мозес, Kemerovo State Medical University

assistant of the department of polyclinic therapy and nursing

References

Diolombi ML, Cheng L, Argani P, Epstein JI. Do Clear Cell Papillary Renal Cell Carcinomas Have Malignant Potential? Am J Surg Pathol. 2015; 39(12): 1621-1634. DOI: 10.1097/PAS.0000000000000513

Leroy X, Camparo P, Gnemmi V, Aubert S, Flamand V, Roupret M, et al. Clear cell papillary renal cell carcinoma is an indolent and low-grade neoplasm with overexpression of cyclin-D1. Histopathology. 2014; 64(7): 1032-1036. DOI: 10.1111/his.12359

Bokhyan VU, Pavlovskaya AI, Kolomeitseva AA, Bugaev VE, StilidiRussian IS. Indolent form of adrenocortical carcinoma: clinico-morphological features of 7 patients. Endocrine surgery. 2016; 10(4): 13-19. Russian (Бохян В.Ю., Павловская А.И., Коломейцева А.А., Бугаёв В.Е., Стилиди И.С. Индолентное течение адренокортикального рака: клинико-морфологическая характеристика 7 больных //Эндокринная хирургия. 2016. Т. 10, № 4. С. 13-19.) DOI: 10.14341/serg2016413-19

Surgical diseases: textbook /ed. AF Chernousova, VF Vetsheva, SP Vetshev. M.: Practical medicine, 2017. 504 p. Russian (Хирургические болезни: учебник /под ред. А.Ф. Черноусова, В.Ф. Ветшева, С.П. Ветшева. М.: Практическая медицина, 2017. 504 с.)

Ushakova GA, Elgina SI. Methodology and organization of prevention of violations of the formation of the reproductive system of girls. Pediatric and adolescent reproductive health. 2008; 6: 29-35. Russia (Ушакова Г.А., Елгина С.И. Методология и организация профилактики нарушений формирования репродуктивной системы девочек //Репродуктивное здоровье детей и подростков. 2008. № 6. С. 29-35)

Wang C, Sun Y, Wu H, Zhao D, Chen J. Distinguishing adrenal cortical carcinomas and adenomas: a study of clinicopathological features and biomarkers. Histopathology. 2014; 64(4): 567-576. DOI: 10.1111/his.12283

Williams AR, Hammer GD, Else T. Transcutaneous biopsy of adrenocortical carcinoma is rarely helpful in diagnosis, potentially harmful, but does not affect patient outcome. Eur J Endocrinol. 2014; 170(6): 829-835. DOI: 10.1530/EJE-13-1033

Launay N, Silvera S, Tenenbaum F, Groussin L, Tissier F, Audureau E, et al. Value of 18-F-FDG PET/CT and CT in the Diagnosis of Indeterminate Adrenal Masses. Int J Endocrinol. 2015; 2015: 213875. DOI: 10.1155/2015/213875

Elgina SI. Clinical evaluation of neonatal girls' reproductive system and prognosis of its formation disturbances. Pediatric and adolescent reproductive health. 2009; 1: 43-47. Russia (Елгина С.И. Клиническая оценка репродуктивной системы новорожденных девочек и прогнозирование нарушений ее становления //Репродуктивное здоровье детей и подростков. 2009. № 1. С. 43-47)

Takeuchi S, Balachandran A, Habra MA, Phan AT, Bassett RL, Macapinlac HA, Chuang HH. Impact of ¹⁸F-FDG PET/CT on the management of adrenocortical carcinoma: analysis of 106 patients. Eur J Nucl Med Mol Imaging. 2014; 41(11): 2066-2073. DOI: 10.1007/s00259-014-2834-3

Asare EA, Wang TS, Winchester DP, Mallin K, Kebebew E, Sturgeon C. A novel staging system for adrenocortical carcinoma better predicts survival in patients with stage I/II disease. Surgery. 2014; 156(6): 1378-1385. DOI: 10.1016/j.surg.2014.08.018

Livhits M, Li N, Yeh MW, Harari A. Surgery is associated with improved survival for adrenocortical cancer, even in metastatic disease. Surgery. 2014; 156(6): 1531-1540. DOI: 10.1016/j.surg.2014.08.047

Livhits M, Li N, Yeh MW, Harari A. Surgery is associated with improved survival for adrenocortical cancer, even in metastatic disease. Surgery. 2014; 156(6): 1531-1540. DOI: 10.1016/j.surg.2014.08.047

Bezerra JE, Latronico AC. MicroRNA era: the importance for diagnosis and prognosis of adrenocortical tumors. Biomed Res Int. 2014; 2014: 381917. DOI: 10.1155/2014/381917

Aufforth RD, Nilubol N. Emerging therapy for adrenocortical carcinoma. Int J Endocr Oncol. 2014; 1(2): 173-182. DOI: 10.2217/ije.14.13

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