NEAR MISS: CLINICAL CASES OF COVID-19 OUTCOME IN PATIENTS WITH COMPLEX COAGULOPATHY

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CASE HISTORY
Published:
2023-08-15
DOI:
https://doi.org/10.24412/2687-0053-2023-3-70-74

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Татьяна Владимировна Мироненко
Kuzbass Regional Clinical Hospital named after S.V. Belyaev, Kemerovo
Орлан Валерьевич Ооржак
Kuzbass Regional Clinical Hospital named after S.V. Belyaev, Kemerovo
Александр Карлович Лейсле
Kuzbass Regional Clinical Hospital named after S.V. Belyaev, Kemerovo
Евгений Владимирович Довбета
Kuzbass Regional Clinical Hospital named after S.V. Belyaev, Kemerovo
Елена Владимировна Рудаева
Kemerovo State Medical University
Вадим Гельевич Мозес
Kemerovo State University; Kuzbass Clinical Hospital named after S.V. Belyaev, Kemerovo
Светлана Ивановна Елгина
Kemerovo State Medical University
Кира Борисовна Мозес
Kemerovo State Medical University
Сергей Валерьевич Рыбников
Kemerovo State Medical University
Яэль Центер
Soroka Medical Center, Beer Sheva

Abstract

COVID-19 leads to a cytokine storm, a systemic inflammatory response, and coagulopathy, which is one of the worst prognostic factors. Coagulopathy in COVID-19 is accompanied by a pronounced increase in D-dimer and fibrin/fibrinogen breakdown products, while deviations in other parameters (prothrombin time, activated partial thromboplastin time, platelet count) at the onset of the disease are relatively rare. For coagulopathy associated with COVID-19, empiric anticoagulant therapy aimed at preventing venous thrombosis and thromboembolism, as well as standard maintenance therapy for sepsis-induced coagulopathy or disseminated intravascular coagulation syndrome, should be carried out.

Keywords

COVID-19, bleeding disorders, coagulopathy, DIC, anticoagulant therapy, prevention

Author Biographies

Татьяна Владимировна Мироненко,
candidate of medical sciences, surgeon, department of surgery N 1
Орлан Валерьевич Ооржак,
, candidate of medical sciences, head of surgical department N 1
Александр Карлович Лейсле,
candidate of medical sciences, radiologist, X-ray department N 1
Евгений Владимирович Довбета,
surgeon, department of surgery N 1
Елена Владимировна Рудаева,
candidate of medical sciences, docent, docent of the department of obstetrics and gynecology named after G.A. Ushakova
Вадим Гельевич Мозес,
doctor of medical sciences, docent, director of the Medical Institute; deputy chief physician for research activities
Светлана Ивановна Елгина,
doctor of medical sciences, docent, professor of department of obstetrics and gynecology N 1
Кира Борисовна Мозес,
assistant, department of polyclinic therapy and nursing
Сергей Валерьевич Рыбников,
doctor of medical sciences, professor of the department of obstetrics and gynecology named after G.A. Ushakova
Яэль Центер,
pathologist

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.
© Татьяна Владимировна Мироненко, Орлан Валерьевич Ооржак, Александр Карлович Лейсле, Евгений Владимирович Довбета, Елена Владимировна Рудаева, Вадим Гельевич Мозес, Светлана Ивановна Елгина, Кира Борисовна Мозес, Сергей Валерьевич Рыбников, Яэль Центер, 2023


Creative Commons License  This work is licensed under a Creative Commons Attribution 4.0 License.

How to Cite

Мироненко, Т. В., Ооржак, О. В., Лейсле, А. К., Довбета, Е. В., Рудаева, Е. В., Мозес, В. Г., Елгина, С. И., Мозес, К. Б., Рыбников, С. В., & Центер, Я. (2023). NEAR MISS: CLINICAL CASES OF COVID-19 OUTCOME IN PATIENTS WITH COMPLEX COAGULOPATHY. Medicine in Kuzbass, 22(3), 70-74. https://doi.org/10.24412/2687-0053-2023-3-70-74

References

Interim Guidelines: Prevention, Diagnosis, and Treatment of Novel Coronavirus Infection (COVID-19). Ministry of Health of Russia. Version 16 (08/18/2022). 249 p. Russian (Временные методические рекомендации: профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Минздрав России. Версия 16 (18.08.2022). 249 с.)

Anaev EKh, Knyazheskaya NP. Coagulopathy in COVID-19: focus on anticoagulant therapy. Practical pulmonology. 2020; 1: 3-13. Russian (Анаев Э.Х., Княжеская Н.П. Коагулопатия при COVID-19: фокус на антикоагулянтную терапию //Практическая пульмонология. 2020. № 1. С. 3-13)

Galstyan GM. Coagulopathy in COVID-19. Pulmonologiya. 2020; 30(5): 645-657. Russian (Галстян Г.М. Коагулопатия при COVID-19 //Пульмонология. 2020. Т. 30, № 5. C. 645-657.) doi.org/10.18093/0869-0189-2020-30-5-645-657

Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020; 18(4): 844-847. doi: 10.1111/jth.14768

Zhang Y, Xiao M, Zhang S, Xia P, Cao W, Jiang W, et al. Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19. N Engl J Med. 2020; 382(17): e38. doi: 10.1056/NEJMc2007575

Franchini M, Marano G, Cruciani M, Mengoli C, Pati I, Masiello F, et al. COVID-19-associated coagulopathy. Diagnosis (Berl). 2020; 7(4): 357-363. doi: 10.1515/dx-2020-0078

Jayarangaiah A, Kariyanna PT, Chen X, Jayarangaiah A, Kumar A. COVID-19-Associated Coagulopathy: An Exacerbated Immunothrombosis Response. Clin Appl Thromb Hemost. 2020; 26: 1076029620943293. doi: 10.1177/1076029620943293

Colling ME, Kanthi Y. COVID-19-associated coagulopathy: An exploration of mechanisms. Vasc Med. 2020; 25(5): 471-478. doi: 10.1177/1358863X20932640

Spiezia L, Boscolo A, Poletto F, Cerruti L, Tiberio I, Campello E, et al. COVID-19-Related Severe Hypercoagulability in Patients Admitted to Intensive Care Unit for Acute Respiratory Failure. Thromb Haemost. 2020; 120(6): 998-1000. doi: 10.1055/s-0040-1710018

Helms J, Tacquard C, Severac F, Leonard-Lorant I, Ohana M, Delabranche X, et al. High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study. Intensive Care Med. 2020; 46(6): 1089-1098. doi: 10.1007/s00134-020-06062-x

Panigada M, Bottino N, Tagliabue P, Grasselli G, Novembrino C, Chantarangkul V, et al. Hypercoagulability of COVID-19 patients in intensive care unit. A report of thromboelastography findings and other parameters of hemostasis. J Thromb Haemost. 2020; 18(7): 1738-1742. doi: 10.1111/jth.14850

Frantzeskaki F, Armaganidis A, Orfanos SE. Immunothrombosis in Acute Respiratory Distress Syndrome: Cross Talks between Inflammation and Coagulation. Respiration. 2017; 93(3): 212-225. doi: 10.1159/000453002

Middeldorp S, Coppens M, van Haaps TF, Foppen M, Vlaa AP r, Müller MCA, et al. Incidence of venous thromboembolism in hospitalized patients with COVID-19. Thromb Haemost. 2020; 18(8): 1995-2002. doi: 10.1111/jth.14888

Fox SE, Akmatbekov A, Harbert JL, Li G, Brown JQ, Heide RSV. Pulmonary and cardiac pathology in African American patients with COVID-19: An autopsy series from New Orleans. Lancet Respir Med. 2020; 8(7): 681-686. doi: 10.1016/S2213-2600(20)30243-5

Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T, et al. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res. 2020; 191: 9-14. doi: 10.1016/j.thromres.2020.04.024

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