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Игорь Васильевич Малов
Леонид Николаевич Иванов
Марина Леонидовна Колотилова
Антонина Вячеславовна Карпунина

Abstract

In order to assess the effectiveness of the use of zeolite tripoli, groups of animals were formed depending on the use of this mineral, as well as the presence of a cariogenic diet. As a result, four groups of laboratory rats were included in the work. The first group included 26 rats fed the basic feed. The second group (n = 26) consisted of animals, which, together with the basic feed, received a zeolite-containing tripoli in the amount of 1.5 g per kilogram of body weight in addition to the standard diet. The third group (n = 26) was on a cariesogenic diet, and the fourth group (n = 26) was on a cariogenic diet; however, the rats of this group, together with the basic feed, were also given a zeolite tripoliin the amount of 1.5 g per kilogram of body weight.

At the initial stage of the experiment, laboratory animals did not differ significantly from each other. However, after the experiment, we identified certain differences that indicate the effectiveness of the use of zeolite-containing Tripoli. Analysis of the biochemical parameters of the gums revealed statistically significant differences with respect to the data series. The effect of zeolite-containing Tripoli on the concentration of malonic dialdehyde, the total proteolytic activity of catalase and urease has been established. The data on the positive effect of zeolite trefoil on the biochemical parameters of blood, gums, as well as the content of saliva minerals were obtained. The above data are consistent with the results of the morphological study of the teeth of the studied animals.

Keywords

caries, zeolite-containing Tripoli, biochemical parametersof blood and gums, saliva minerals, cariesogenic diet

Author Biographies

Игорь Васильевич Малов,
assistant, department of therapeutic dentistry
Леонид Николаевич Иванов,
doctor of medical sciences, professor, department of normal and pathological physiology
Марина Леонидовна Колотилова,
doctor of medical sciences, docent, professor of the department of human pathology, Institute of Clinical Medicine named after N.V. Sklifosovsky
Антонина Вячеславовна Карпунина,
candidate of medical sciences, docent of the department of therapeutic dentistry

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.

How to Cite

Малов, И. В., Иванов, Л. Н., Колотилова, М. Л., & Карпунина, А. В. (2020). ZEOLITE-CONTAINING THRILL IN THE PREVENTIVE TREATMENT OF EXPERIMENTAL CARIES. Medicine in Kuzbass, 19(4), 5-13. https://doi.org/10.24411/2687-0053-2020-10033

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