COMPARATIVE EVALUATION OF INFLAMMATORY RESPONSE IN DIFFERENT TYPES OF ANESTHESIA FOR COLON CANCERSURGERY
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Abstract
Objective – to evaluate the inflammatory response within the first 24 hours postoperative period in patients who underwent resection surgery for colon cancer under different types of anesthesia.
Methods: laboratory, statistics.
Results. Levels of interleukin 6, 10, C-reactive protein in the blood of patients operated on for colon cancer under multicomponent multimodal anesthesia, analgesia and superficial sympathetic blockade in the first 24 postoperative hours are higher than in patients operated on under inhalation-intravenous anesthesia and systemic pain relief after the surgery. Levels of interleukin 6, 10, C-reactive protein in the blood of patients operated on for colon cancer under multicomponent multimodal anesthesia, analgesia and superficial sympathetic blockade, supplemented with local infiltration anesthesia, are lower than those of patients operated under the same type of anesthesia-analgesia, but without the local infiltration anesthesia.
Conclusions. Superficial sympathetic blockade enhances and local infiltration anesthesia reduces the inflammatory response early after the resection surgery for colon cancer, keeping all advantages of multimodal analgesia-anesthesia as an effective means of protection against surgical stress.
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The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.
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