A CASE OF ANEMBRYONIC PREGNANCY DUE TO INHERITED CHROMOSOMAL ABNORMALITY: ON THE NEED FOR CYTOGENETIC EXAMINATION OF PARTNERS IN CASE OF INFERTILITY IN MARRIAGE
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Abstract
We performed a medical genetic analysis of a case of anembryonic pregnancy resulting from an inherited chromosomal abnormality. For this purpose, cytogenetic study of biopsy material from non-developing pregnancy and peripheral blood samples of spouses was accomplished. In the karyotype of abortion had been found an additional derivative chromosome der(14;22)(q10;q10), which caused anembryonic pregnancy. Examination of the spouses established the paternal origin of the chromosomal abnormality. Case analysis highlights the need for cytogenetic examination of both abortions and marital partners in reproductive failures. The result of the study will make it possible to determine the optimal tactics for solving the problem of marital infertility.
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