PECULIARITIES OF AUTONOMOUS REGULATION IN THE PATIENTS WITH SYNCOPE LIVING IN AN INDUSTRIAL CITY
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Abstract
Subject. Changes in heart rate variability and systemic hemodynamics in orthostasis in the patients with neurogenic syncope living in an industrial city.
Objective. To reveal disturbances of autonomous regulation in the patients with syncope at a young age for early conducting pathophysiologically substantiated therapeutic and preventive measures.
Methods. In the young patients with neurogenic syncope who are the residents of Novokuznetsk spectral, statistical and non-linear indices of heart rate variability were determined at the stages of an active orthostatic test. Their dynamics in the sample was assessed taking into account the changes in the indices of systemic hemodynamics and data obtained in the control group.
Results. In the residents of an industrial city, the disturbance of sympathetic regulation was determined already at a young age, increasing the risk of early development of cardiovascular diseases. Changes in the power of various parameters of the spectrum of heart rate variability during an orthostatic test make it possible to evaluate compensatory mechanisms for maintaining an adequate level of systemic circulation.
Conclusions. Taking into account the changes in the spectral indices of heart rate variability during an active orthostatic test, a pathogenetic approach to the early detection, treatment and prevention of cardiovascular diseases is possible.Keywords
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Shen WK, Sheldon RS, Benditt DG, Cohen MI, Forman DE, Goldberger ZD et al. ACC/AHA/HRS Guideline for the evaluation and management of patients with syncope: a report of the American College of Cardiology / American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2017 Aug 1; 70(5): e39-e110
Moya A, Sutton R, Ammirati F et al. Guidelines for the diagnosis and management of syncope (version 2009) / the Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC). Eur Heart J. 2009; (21): 2631-2671
Martynov ID, Fleishman AN. Disturbances of autonomous regulation and compensatory possibilities at orthostatic loads in the patients with neurogenic syncope (based on the spectral analysis of heart rate variability). Herald of science of Siberia. 2015; (1): 303-313. Russian (Мартынов И.Д., Флейшман А.Н. Нарушения вегетативной регуляции и компенсаторные возможности при ортостатических нагрузках у больных с нейрогенными обмороками (на основе спектрального анализа вариабельности ритма сердца) //Вестник науки Сибири. 2015. № 1. С. 303-313)
Syncope in clinical practice. Shutov SB, editor. St. Petersburg, 2009. 336 p. Russian (Синкопальные состояния в клинической практике /под ред. С.Б. Шутова. СПб., 2009. 336 с.)
Mikhailov VM. Heart rate variability. Experience of practical application. Ivanovo, 2000. 200 p. Russian (Михайлов В.М. Вариабельность ритма сердца. Опыт практического применения. Иваново, 2000. 200 с.)
Baevsky RM, Ivanov GG, Gavrilushkin AP, Dovgalevsky PYa, Kukushkin YuA, Mironova TF et al. Analysis of heart rate variability using different electrocardiographic systems. Part 1. Herald of arrhythmology. 2002; (24): 65-86. Russian (Баевский Р.М., Иванов Г.Г., Гаврилушкин А.П., Довгалевский П.Я., Кукушкин Ю.А., Миронова Т.Ф. и др. Анализ вариабельности сердечного ритма при использовании различных электрокардиографических систем. Часть 1 //Вестник аритмологии. 2002. № 24. С. 65-86)
Shvalev VN, Reutov VP, Sergienko VB, Rogoza AN, Masenko VP, Ansheles AA. Mechanisms of the development of cardiac diseases in age-related disorders of the nervous system. Kazan medical journal. 2016; 97(4): 598-606. Russian (Швалев В.Н., Реутов В.П., Сергиенко В.Б., Рогоза А.Н., Масенко В.П., Аншелес А.А. Механизмы развития кардиологических заболеваний при возрастных нарушениях состояния нервной системы //Казанский медицинский журнал. 2016. Т. 97, № 4. С. 598-606)
Albitskaya KV, Kuchinskaya EA, Kheimets GI, Loladze NV, Pevzner AV, Rogoza AN et al. State of myocardial sympathetic innervation according to the data of isotope scanning with 123I-metaiodobenzyl guanidine in patients with vasovagal syncope. Herald of arrhythmology. 2007; (50): 11-15. Russian (Альбицкая К.В., Кучинская Е.А., Хеймец Г.И., Лоладзе Н.В., Певзнер А.В., Рогоза А.Н. и др. Состояние симпатической иннервации миокарда по данным сцинтиграфии 1231-метайодбензилгуанедином у пациентов с вазовагальными обмороками //Вестник аритмологии. 2007. № 50. С. 11-15)
Pogodina AV, Dolgikh VV, Valyavskaya OV. Electrocardiography patterns of tilt-induced cardioinhibitory syncope in children and adolescent. Russian cardiology journal. 2012; (2): 49-54. Russian (Погодина А.В., Долгих В.В., Велявская О.В. Электрокардиологическая характеристика тилт-индуцированных кардиоингибиторных обмороков у детей и подростков //Российский кардиологический журнал. 2012. № 2. С. 49-54)
Guidelines to cardiology in four volumes. Vol. 1. Physiology and pathophysiology of the cardiovascular system. Chazov EI, editor. Moscow: Practice Publ., 2014. 395 p. Russian (Руководство по кардиологии в четырех томах. Т. 1. Физиология и патофизиология сердечно-сосудистой системы /под ред. Е.И. Чазова. М.: Практика, 2014. 395 с.)