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Алексей Андреевич Шмелев
Алексей Геннадьевич Тришкин
Антон Игоревич Лесников
Лилия Владиславовна Курганова
Алексей Дмитриевич Бушмакин
Алексей Сергеевич Ильин

Abstract

The immunological factor is one of the causes of male infertility. If there is a significant amount of sperm in the ejaculate that is sensitive to antisperm antibodies (ASAT), the ability to fertilize may be impaired. Antibodies directed against sperm components have a negative effect on various processes before and after fertilization.
Objective – to identify the prevalence of the immunological factor in men of the Kemerovo region. Compare the spermogram indicators in men with different indicators of the MAR test.
Results. It was found out that out of 1827 men with infertility, a positive MAR test was detected in 116, which was 6.35 % of the sample. The negative effect of ASAT on concentration and progressive mobility was demonstrated in the comparison group between a high (90-100 %) and normal (less than 40 %) MAR test index.
Conclusion. The prevalence of the immunological factor of infertility in Kuzbass men has been revealed. A difference was found between the indicators of concentration and progressive motility of spermatozoa in the groups with normal and high values of the MAR test.

Keywords

male infertility, immunological factor, spermogram parameters, antisperm antibodies, MAR test

Author Biographies

Алексей Андреевич Шмелев,
postgraduate student of the department of new reproductive technologies; biologist
Алексей Геннадьевич Тришкин,
doctor of medical sciences, head of the department of new reproductive technologies; head of the ART department
Антон Игоревич Лесников,
assistant, department of new reproductive technologies; biologist-embryologist
Лилия Владиславовна Курганова,
assistant, department of new reproductive technologies; biologist-embryologist, head of the embryological laboratory
Алексей Дмитриевич Бушмакин,
assistant, department of new reproductive technologies; urologist-andrologist
Алексей Сергеевич Ильин,
biologist

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.

How to Cite

Шмелев, А. А., Тришкин, А. Г., Лесников, А. И., Курганова, Л. В., Бушмакин, А. Д., & Ильин, А. С. (2024). IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGION. Medicine in Kuzbass, 23(2), 68-71. https://doi.org/10.24412/2687-0053-2024-2-68-71

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