Main Article Content
Abstract
The aim of the research. Identify the main risk factors affecting the formation of fetal growth retardation (FGR).
Material and methods. A retrospective cohort study of 263 birth histories for 2019 was conducted on the basis of the City Clinical Perinatal Center BUZOO in Omsk. The main group consisted of 148 women who gave birth to children with an established diagnosis of FGR. This group was divided into 2 subgroups: the main 1 – 82 women with full-term pregnancy; the main 2 – 66 pregnant women with preterm birth (PB). The control group consisted of 115 women whose urgent delivery ended in the birth of a full-term baby with normal body weight.
Results. FGR is more often formed in women with adverse socio-economic factors (working in industries associated with severe physical exertion, living in an uncomfortable environment with harmful effects, with a low economic status, experiencing psycho-emotional stress, and familiar chronic intoxications). Also, FGR was more often detected in pregnant women with a burdened obstetric history (spontaneous miscarriages, preeclampsia, PB, intrahepatic cholestasis), with infectious diseases (with full-term pregnancy in 19.5 %, with PB in 21.2 %); cardiovascular diseases were more common in patients with FGR and PB (39.4 %). In the structure of gynecological diseases in the history of pregnant women with FGR, bacterial vaginitis was in the lead (19.5 % in full-term pregnancy, 27.3 % in PB). In second place, women with PB had uterine fibroids.
Conclusion. Among the complications of pregnancy in women with FGR, edema and hypertensive disorders, which threatened spontaneous miscarriage, were more often diagnosed. In the group of women with preterm birth, placental disorders, congenital infection and gestational diabetes were leading.
Keywords
Article Details
Information about financing and conflict of interests
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.
This work is licensed under a Creative Commons Attribution 4.0 License.
How to Cite
References
Gardosi J, Madurasinghe V, Williams M, Malik A, Francis A. Maternal and fetal risk factors for stillbirth: population based study. BMJ. 2013; 346: f108. doi: https://doi.org/10.1136/bmj.f108
Mayer C, Joseph KS. Fetal growth: a review of terms, concepts and issues relevant to obstetrics. Ultrasound Obstet. Gynecol. 2013; 41(2): 136-145. doi: 10.1002/uog.11204
Voskamp BJ, Kazemier BM, Ravelli AC, Schaaf J, Mol BW, Pajkrt E. Recurrence of small-for-gestational-age pregnancy: analysis of first and subsequent singleton pregnancies in The Netherlands. Am J Obstet Gynecol. 2013; 208(5): 374.e1-6. doi: 10.1016/j.ajog.2013.01.045
Wijs LA, de Graaff EC, Leemaqz S, Dekker G. Causes of stillbirth in a socioeconomically disadvantaged urban Australian population – a comprehensive analysis. J Matern Fetal Neonatal Med. 2017; 30(23): 2851-2857. doi: 10.1080/14767058.2016.1265933
Resnik R, Lockwood CJ, Levine D, Barss VA. Fetal growth restriction. Evaluation and management. UCSD School of Medicine; 2016. Available at: http://www.uptodate.com/contents/fetal-growth-restricition-evaluation-and-management?source=search_result&search=IUGR&selectedTitle=1%7E150
Strizhakov AN, Miryushchenko MM, Ignatko IV, Popova NG, Florova VS, Kuznecov AS. Predicting fetal growth retardation syndrome in high-risk pregnant women. Obstetrics and gynecology. 2017; 7: 34-44. Russian (Стрижаков А.Н., Мирющенко М.М., Игнатко И.В., Попова Н.Г., Флорова В.С., Кузнецов А.С. Прогнозирование синдрома задержки роста плода у беременных высокого риска //Акушерство и гинекология. 2017. № 7. С. 34-44.) doi: 10.18565/aig.2017.7.34-44
Bashmakova NV, Cyv'yan PB, CHistyakova GN, Dan'kova IV, Trapeznikova YUM, CHukanova AN. The role of endothelial dysfunction in the onset of fetal growth retardation syndrome. Russian Bulletin of Obstetrician-Gynecologist. 2017; 17(3): 21-26. Russian (Башмакова Н.В., Цывьян П.Б., Чистякова Г.Н., Данькова И.В., Трапезникова Ю.М., Чуканова А.Н. Роль дисфункции эндотелия в возникновении синдрома задержки роста плода //Российский вестник акушера-гинеколога. 2017. Т. 17, № 3. С. 21-26.) doi: 10.17116/rosakush201717321-26
Nardozza LM, Caetano AC, Zamarian AC, Mazzola JB, Silva CP, Margal VM et al. Fetal Growth Restriction: Current Knowledge. Arch Gynecol Obstet. 2017; 295(5): 1061-1077. doi: 10.1007/s00404-017-4341-9
Belocerkovceva LD, Kasparova AE, Kovalenko LV, Mordovina II, Naumova LA. Chromosomal pathology and early preeclampsia in pregnancy outcomes with progressive placental insufficiency. Vestnik SurGU. Medicina. 2019; 1: 26-33. Russian (Белоцерковцева Л.Д., Каспарова А.Э., Коваленко Л.В., Мордовина И.И., Наумова Л.А. Хромосомная патология и ранняя преэклампсия в исходах беременности с прогрессирующей плацентарной недостаточностью //Вестник СурГУ. Медицина. 2019. № 1. С. 26-33)
Kesavan K, Devaskar SU. Intrauterine Growth Restriction: Postnatal Monitoring and Outcomes. Pediatr Clin North Am. 2019; 66(2): 403-423. doi: 10.1016/j.pcl.2018.12.009
Vaiserman AM. Birth weight predicts aging trajectory: A hypothesis. Mech Ageing Dev. 2018; 173: 61-70. doi: 10.1016/j.mad.2018.04.003
Beznoshchenko GB, Kravchenko EN, Kuklina LV, Kropmaer KP, Beznoshchenko AB, Safonova ES. Fetal growth Retardation: risk factors and prognosis. Tavricheskij mediko-biologicheskij vestnik. 2016; 19(2): 18-21. Russian (Безнощенко Г.Б., Кравченко Е.Н., Куклина Л.В., Кропмаер К.П., Безнощенко А.Б., Сафонова Е.С. Задержка роста плода: факторы риска и прогнозирование //Таврический медико-биологический вестник. 2016. Т. 19. № 2. С. 18-21)
Beznoshchenko GB, Kravchenko EN, Rogova EV, Lyubavina AE, Kuklina LV. Placental insufficiency and placental region condition in pregnant women with preeclampsia. Russian Bulletin of Obstetrician-Gynecologist. 2014; 14(5): 4-8. Russian (Безнощенко Г.Б., Кравченко Е.Н., Рогова Е.В., Любавина А.Е., Куклина Л.В. Плацентарная недостаточность и состояние плацентарной области у беременных с преэклампсией //Российский вестник акушера-гинеколога. 2014. Т. 14, № 5. С. 4-8)
Beznoshchenko GB, Kravchenko EN, Cukanov YuG, Kropmaer KP, Cygankova OYu, Vladimirova MP. Placental disorders and venous insufficiency. Russian Bulletin of Obstetrician-Gynecologist. 2015; 15(5): 50-55. Russian (Безнощенко Г.Б., Кравченко Е.Н., Цуканов Ю.Г., Кропмаер К.П., Цыганкова О.Ю., Владимирова М.П. Плацентарные нарушения и венозная недостаточность //Российский вестник акушера-гинеколога. 2015. Т. 15, № 5. С. 50-55)
Kravchenko EN, Gordeeva IA. Features of the course of labor in asymptomatic bacteriuria in pregnant women: practical experience and therapeutic aspects. Gynecology. 2014;16(2):78-81. Russian (Кравченко Е.Н., Гордеева И.А. Особенности течения родов при бессимптомной бактериурии у беременных: практический опыт и лечебные аспекты //Гинекология. 2014. Т.16, № 2. С. 78-81)
