RISK FACTORS FOR VERY PRETERM DELIVERY
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Abstract
The aim of the research – assess risk factors for very preterm delivery in the Omsk region.
Materials and methods. The main group comprised women with very preterm delivery (n = 64); сomparison group – pregnant women with a threat of interruption in terms of 22-27 weeks and successful preserving therapy (n = 63); control group – pregnant women in whom this pregnancy was taking place without the threat of interruption (n = 62).
Results. Risk factors for very preterm delivery were bacterial vaginosis, specific vaginitis, kidney disease and the threat of interruption. There was a significant lead in streptococci (32.3 ± 5.8 %), especially group B (19.0 ± 4.9 %) in the main group. The risk factor for very preterm delivery was infectious viral diseases transferred during pregnancy, observed in 12.7 ± 4.2 % of women in the main group, in 7.8 ± 3.3 % in the comparison group (p < 0.01) and in 4.8 ± 2,7 % – control (p < 0,001). In the main group, placental insufficiency was 2 times more common than in the comparison group and 13 times than in the control group. Every sixth pregnant of the main group had manifestations of gestosis. Such complications of gestation as the premature detachment of the normally inserted placenta (7.8 ± 3.3 %) and inborn malformations of a fruit (1.6 ± 1.6 %) were observed only in the main group.
Conclusion. The results of the research and literature data showed that the significant influence on the level of very early premature births is due to: the age of the parents, the abuse of nicotine, alcohol, drugs, abortion, preterm birth, urinary tract and genital tract infections, severe somatic diseases, multiple pregnancies. In the structure of complications of gestation during miscarriages, placental insufficiency predominates, the threat of abortion, fetal growth retardation, and polyhydramnios.
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Bashmakova NV, Kayumova AV, Melkozerova OA. Analysis of the management of preterm births, ending with the birth of children with ENMT. The first experience in the era of new live birth criteria. Оbstetrics and Gynecology. 2013; 6: 41-45. Russian (Башмакова Н.В., Каюмова А.В., Мелкозерова О.А. Анализ ведения преждевременных родов, закончившихся рождением детей с ЭНМТ. Первый опыт в эру новых критериев живорождения //Акушерство и гинекология. 2013. № 6. С. 41-45)
Tebelev BG, Dyatlova LI, Abrosimova LV, Donguzova YeV. Influence on pregnancy and premature newborns of placental inflammation. International Journal of Applied and Fundamental Research. 2014; 5(2): 78-80. Russian (Тебелев Б.Г., Дятлова Л.И., Абросимова Л.В., Донгузова Е.В. Влияние на беременность и недоношенных новорожденных воспаления плаценты //Международный журнал прикладных и фундаментальных исследований. 2014. № 5(2). С. 78-80)
Kostin IN, Messiya NV, Zamotina IV. The treatment of cervical incompetence in the second trimestr of pregnancy: review. Surgeon. 2014; 6: 84-90. Russian (Костин И.Н., Мессия Н.В., Замотина И.В. Коррекция истмико-цервикальной недостаточности во II триместре беременности (обзор литературы) //Хирург. 2014. № 6. С. 84-90)
Kravchenko YeN, Sinitsyna SS, Lyubavina AYe. Pathogenetic moments of very early premature births with ascending infection of the afterbirth. Mother and Baby in Kuzbass. 2011; 1: 50-54. Russian (Кравченко Е.Н., Синицына С.С., Любавина А.Е Патогенетические моменты очень ранних преждевременных родов при восходящем инфицировании последа //Мать и Дитя в Кузбасе. 2011. № 1. C. 50-54)
Kravchenko YeN, Sinitsyna SS, Mishutina AV. On the issue of the transition to the international criteria for the registration of the birth of children in the subjects of the Russian Federation on the example of the Omsk region. Health of the Russian Federation. 2012; 5: 37-40. Russian (Кравченко Е.Н., Синицына С.С., Мишутина А.В. К вопросу о переходе на международные критерии регистрации рождения детей в субъектах Российской федерации на примере Омской области //Здравоохранение Российской Федерации. 2012. № 5. С. 37-40)
Novakovskaya YaF. Analysis of the causes and outcomes of early premature births. Bulletin of medical Internet conferences. 2014; 4(5): 447. Russian (Новаковская Я.Ф. Анализ причин и исходов ранних преждевременных родов //Бюллетень медицинских Интернет-конференций. 2014. Т. 4, № 5. С. 447)
Kravchenko YeN, Sinitsyna SS, Mishutina AV. Features of the course of pregnancy and the outcome of childbirth with extremely low fetal body mass. The Russian Bulletin of the Obstetrician-Gynecologist. 2012; 12(5): 44-48. Russian (Кравченко Е.Н., Синицына С.С., Мишутина А.В. Особенности течения беременности и исход родов при экстремально низкой массе тела плода //Российский вестник акушера-гинеколога. 2012. Т. 12, № 5. С. 44-48)
Kazemier BM, Buijs PE, Mignini L, Limpens J, de Groot CJ, Mol BW. Impact of obstetric history on the risk of spontaneous preterm birth in singleton and multiple pregnancies: a systematic review. BJOG. 2014; 121(10): 1197-1208. doi: 10.1111/1471-0528.12896
Kuz'min VN, Murriyeva GA. Importance of polymorphism and expression of cytokine genes in forecasting the risk of preterm delivery. Lechashhij vrach. 2013; 11: 26. Russian (Кузьмин В.Н., Мурриева Г.А. Значение полиморфизма и экспрессии генов цитокинов в прогнозировании риска преждевременных родов //Лечащий врач. 2013. № 11. С. 26)
Kravchenko YeN, Mishutina AV, Sinitsyna SS, Zyryanova IN, Batyreva NV. Influence of infection on the initiation of labor by a fetus with an extremely low mass. Bulletin of the Peoples' Friendship University of Russia. 2012; 5: 179-186. Russian (Кравченко Е.Н., Мишутина А.В., Синицына С.С., Зырянова И.Н., Батырева Н.В. Влияние инфекции на инициацию родов плодом с экстремально низкой массой //Вестник РУДН. 2012. № 5. С. 179-186)
Malyshkina AI, Pesikin ON, Kuligina MV. The organization of perinatal care in very early premature births in the Central Federal District of the Russian Federation. Obstetrics and Gynecology. 2014; 6: 74-78. Russian (Малышкина А.И., Песикин О.Н., Кулигина М.В. Организация перинатальной помощи при очень ранних преждевременных родах в Центральном Федеральном округе Российской Федерации //Акушерство и гинекология. 2014. № 6. С. 74-78)
Serov VN, Sukhorukova OI. Efficiency of preventive maintenance of premature births. Obstetrics and gynecology. 2013; 3: 48-53. Russian (Серов В.Н., Сухорукова О.И. Эффективность профилактики преждевременных родов //Акушерство и гинекология. 2013. № 3. С. 48-53)
Khodzhayeva ZS, Fedotovskaya OI, Donnikov AYe. Clinical and anamnestic features of women with idiopathic premature births on the exa.mple of the Slav population. Obstetrics and Gynecology. 2014; 3: 28-32. Russian (Ходжаева З.С., Федотовская О.И., Донников А.Е. Клинико-анамнестические особенности женщин с идиопатическими преждевременными родами на примере славянской популяции //Акушерство и гинекология. 2014. № 3. С. 28-32)
Melville JM, Moss TJ. The immune consequences of preterm birth. Front Neurosci. 2013; 7: 79. doi: 10.3389/fnins.2013.00079
Hecht JL, Fichorova RN, Tang VF, Allred EN, McElrath TF, Leviton A. Relationship between neonatal blood protein concentrations and placenta histologic characteristics in extremely low gestation age newborns. Pediatr. Res. 2011; 69(1): 68-73. doi: 10.1203/PDR.0b013e3181fed334