THE DISTRIBUTION AND THE RISK FACTORS OF ASYMPTOMATIC BACTERIURIA OF PREGNANCY IN THE OMSK REGION
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Abstract
Purpose of the study – identification of the prevalence and risk factors of asymptomatic bacteriuria in pregnant women in the Omsk region.
Materials and methods. The results of bacteriological examination of urine samples of 8000 pregnant women were analyzed, then the comparison groups were formed: the main group consisted of 100 patients with diagnosed low-grade asymptomatic bacteriuria who had not been treated; comparison group – 98 pregnant women with asymptomatic bacteriuria 105 CFU/ml; control group: 50 patients without asymptomatic bacteriuria. Statistical processing of the obtained results was carried out by the nonparametric statistics using Statistica 6.1. The reliability of the differences was determined by calculating the χ2 criterion at p < 0.05.
Results. The most frequently detected clinically considered insignificant asymptomatic bacteriuria of 102-104 CFU/ml (12.3 %). Clinically significant bacteriuria with ≥ 105 CFU/ml was detected in 11.3 % of the examined. Moreover, in the first category of patients, especially in combination with risk factors, complications of gestation developed 5.4 times more often than in women with no bacterial growth in bacteriological urine, complications of childbirth and the postpartum period – 7.8 times, pathological changes in placental tissue and membranes – 2 times more often.
Conclusion. Asymptomatic bacteriuria was registered in 23.6 % of the examined patients, and along with clinically significant bacteriuria, a low degree of the urinary tract contamination was also detected. In the presence of clinically insignificant asymptomatic bacteriuria (102-104 CFU/ml), especially in combination with other concomitant risk factors for the development of urinal tract infections (UTI), the complications of the course of pregnancy and childbirth are observed quite often, significantly exceeding the indices not only in the control group but also in the comparison group, that, probably, is connected with obligatoryness of antibacterial therapy at patients with a high degree of bacteriuria.Keywords
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Mignini L. Accuracy of diagnostic tests to detect asymptomatic bacteriuria during pregnancy. Obstet. Gynecol. 2009; 113: 346-352
Christensen B. Which antibiotics are appropriate for treating bacteriuria in pregnancy? J. of Antimicrob. Chemother. 2000; 46(1): 29-34
Quiroga-Feuchter G, Robles-Torres RE, Ruelas-Morán A, Gómez-Alcalá AV. Asymptomatic bacteriuria among pregnant women. An underestimated threat Rev. Med. Inst. Mex. Seguro Soc. 2007; 45(2): 169-172
Sheiner E, Mazor-Drey E, Levy A. Asymptomatic bacteriuria during pregnancy. J. Matern. Fetal. Neonatal. Med. 2009; 22: 423-427
Kravchenko EN, Gordeeva IA, Naumkina EV. Asymptomatic bacteriuria in pregnant women and its complications. News of IAESS in Omsk region. 2014; 1(4): 27-30. Russian (Кравченко Е.Н., Гордеева И.А., Наумкина Е.В. Бессимптомная бактериурия у беременных и ее осложнения //Вести МАНЭБ Омской области. 2014. № 1(4). С. 27-30)
Kravchenko EN, Gordeeva IA, Kolbina MS. Urinary tract infection in pregnant women, treatment and diagnostic aspects. Materials of X International scientific practical conference «Key issues of modern science-2014», April 17-25, 2014, Sofia, T. 26 «Medicine», P. 3-4. Russian (Кравченко Е.Н., Гордеева И.А., Колбина М.С. Инфекции мочевыводящих путей у беременных, лечебно-диагностические аспекты //«Материали за Х Международна научна практична конференция «Ключови въпроси в съвременната наука-2014», 17-25 апреля 2014, г. София, Т. 26 «Лекарство», С. 3-4)
Kravchenko EN, Gordeeva IA. Asymptomatic bacteriuria of pregnant women. In the book: Obstetric Almanac. Ed. EN Kravchenko. Omsk: Publisher «Antares», 2016. P. 248-275. Russian (Кравченко Е.Н., Гордеева И.А. Бессимптомная бактериурия беременных /в кн.: Акушерский альманах /под ред. Е.Н. Кравченко. Омск: Изд-во «Антарес», 2016. С. 248-275)
Kravchenko EN, Gordeeva IA, Naumkina EV. Prevalence, risk factors, complications of asymptomatic bacteriuria in pregnant women. Mother and Baby in Kuzbass. 2014; 2(57): 66-71. Russian (Кравченко Е.Н., Гордеева И.А., Наумкина Е.В. Распространенность, факторы риска, осложнения бессимптомной бактериурии у беременных //Мать и Дитя в Кузбассе. 2014. № 2(57). С. 66-71)
Kravchenko EN, Gordeeva IA. Features of the course of gestation and labor in asymptomatic bacteriuria in pregnant women: practical experience and treatment aspects. Gynecology. 2014; 16(2): 78-82. Russian (Кравченко Е.Н., Гордеева И.А. Особенности течения гестации и родов при бессимптомной бактериурии у беременных: практический опыт и лечебные аспекты //Гинекология. 2014. Т. 16, № 2. С. 78-82)
Kravchenko EN, Gordeeva IA, Kubarev DV. Infectious-inflammatory diseases of the kidneys in pregnant women. Diagnosis and treatment. Obstetrics and gynecology. 2013; 4: 29-32. Russian (Кравченко Е.Н., Гордеева И.А., Кубарев Д.В. Инфекционно-воспалительные заболевания почек у беременных. Диагностика и лечение //Акушерство и гинекология. 2013. № 4. С. 29-32)
Nikonov AP, Ascaturova OR, Kaptilny VA. Urinary tract infection and pregnancy. Gynecology. 2007; 9(1): 38-40. Russian (Никонов А.П., Асцатурова О.Р., Каптильный В.А. Инфекция мочевыводящих путей и беременность //Гинекология. 2007. Т. 9, № 1. С. 38-40)
Smaill F, Vazquez JC. Antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane Database Syst. Rev. 2007; 18(2): CD000490
Anderson BL. Untreated asymptomatic group B streptococcal bacteriuria early in pregnancy and chorioamnionitis at delivery. Am. J. Obstet. Gynecol. 2007; 196(6): 1-5
Nicolle LE. Infectious diseases society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin. Infect. Dis. 2005; 40: 643-654