THE THYMUS GLAND (THYMUS) ASPECTS IN CHILDREN (PART V). HORMONAL AND MORPHOLOGICAL INTERACTION OF THE THYMUS WITH THE NEUROENDOCRINE SYSTEM AND IN PARTICULAR WITH SOMATOTROPIC HORMONE AND INSULIN-LIKE GROWTH FACTOR
Main Article Content
Abstract
The literature review includes data on the interaction of the thymus with the neuroendocrine system, hormonal and morphological relations between the thymus, somatotropic hormone and insulin-like growth factor (IGF), the effect of growth hormone (GH) to age-related thymus involution. The results of experimental studies and contradictory data to the effect of the somatotropic axis (receptor-GR/GR/IGF-1) on thymopoiesis, homeostasis of thymocytes and peripheral T cells are presented.
Keywords
Author Biographies
Наталья Николаевна Миняйлова,
doctor of medical sciences, docent, professor for department of pediatrics and neonatologyЮрий Иванович Ровда,
Rovda Yuryi Ivanovich
MD, PhD, professor
He is the Honoured Doctor of the Russian Federation, the Head of the Department of Pediatrics and Neonatology. He graduated from the Pediatric Faculty of Kemerovo Medical Institute in 1973. On his initiative the Regional Pediatric Cardiac Center was organized. His researches concerning the metabolic syndrome, purinosis, hypertension in children are priorities in the Russian Federation.
He is an expert of the Russian Task Group of Federal Service on Surveillance in Healthcare, dealing with mentioned diseases.
He was the first who developed and implemented method of diagnostics of visceral fat deposition in children with echocardiography and a number of different new scientific-practical methods (the prevention of purine metaboliс imbalance, prenosological diagnostics and prevention of arterial hypertension and metabolic syndrome in children and adolescents, alternative methods of prevention and treatment of metabolic syndrome, allergodermia in children – ozone therapy, etc.).Сергей Фадеевич Зинчук,
candidate of medical sciences, docent, head of the department of morphology and forensic medicineАлександра Евгеньевна Климанова,
clinical resident, department of pediatrics and neonatologyВероника Павловна Строева,
candidate of medical sciences, docent, docent of the department of pediatrics and neonatologyНаталья Степановна Черных,
candidate of medical sciences, docent, docent of the department of polyclinic pediatrics, propaedeutics of children diseases and postgraduate trainingArticle Details
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The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.
This work is licensed under a Creative Commons Attribution 4.0 License.
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References
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