ЭПИДЕМИОЛОГИЧЕСКИЕ ОСОБЕННОСТИ HELICOBACTER PYLORI ИНФЕКЦИИ У ДЕТЕЙ С ЗАБОЛЕВАНИЯМИ ЖЕЛУДОЧНО-КИШЕЧНОГО ТРАКТА, НАХОДЯЩИХСЯ НА СТАЦИОНАРНОМ ЛЕЧЕНИИ

Abstract

Purpose of the study – to determine the epidemiological features of Helicobacter Pylori infection in children with gastrointestinal diseases hospitalized in the gastroenterology department of a multidisciplinary hospital. Materials and methods. A retrospective study of the case histories of 1601 children who were treated in the gastroenterology department in the period 2018-2020 was carried out. All children underwent fibrogastroduodenoscopy with sampling of smears from the gastric mucosa, followed by their Gram staining and microscopy.

Results. Microscopy revealed H. Pylori in 489 patients (30.5%). The frequency of detection of H. Pylory in various pathologies of the gastrointestinal tract was: gastroesophageal reflux with esophagitis (K 21.0) – 39.5 %, chronic superficial gastritis (K 29.3) – 51.35 %, other gastritis (K 29.6) – 2.04 %, chronic cholecystitis (K 81.1) – 0.61 %, other types of Crohn's disease (K 50.8) – 0.4 %, chronic gastric ulcer without bleeding and perforation (K 25.7) – 1.02 %, chronic atrophic gastritis – 2.25 %, chronic gastroduodenitis, unspecified (K 29.9) – 1.43%, gastric ulcer (K 25) – 0.2 %, duodenal ulcer (K 26) – 0.2 %, ulcerative colitis, unspecified (K 21.9) – 0.4 %, fatty liver degeneration, not elsewhere classified (K 76.0) – 0.2 %, chronic hepatitis not elsewhere classified (K 73.0) – 0.4 %.

Conclusions. The results obtained confirm the feasibility of an endoscopic examination with cytological examination of smears and typing for H. Pylori in children with severe gastrointestinal diseases requiring hospital treatment.