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Abstract
The ovarian hyperstimulation syndrome (OHSS) is an iatrogenic syndrome, which may, infrequently, become severe and evenly fatal. Although the milder form is more common, particularly among patients undergoing gonadotropin stimulation for assisted reproductive technology, the severe form is rare.
Unfortunately, there is currently no available way to predict this syndrome. This article aims develop a method for individual prediction of ovarian hyperstimulation syndrome.
The aim of the study is to develop a method for individual prediction of ovarian hyperstimulation syndrome, based on socio-biological data, clinical and laboratory examination data and data obtained during ultrasound examination of the pelvic organs before entering the IVF protocol and during ovulation stimulation.
Materials and methods. An analysis of 671 treatment cycles under the IVF program was carried out, among which 56 cycles were complicated by hyperstimulated ovarian syndrome.
Results and its discussion. The aim of this study was to evaluate risk factors for development ovarian hyperstimulati on syndrome, which we considered in the aggregate with each other. Based on this, a method for individual prediction of the syndrome has been developed.
Conclusions. We have developed a method for individual prediction of ovarian hyperstimulation syndrome with a sensitivity 93.9 %.Keywords
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The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.
This work is licensed under a Creative Commons Attribution 4.0 License.
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References
Alekhina AG, Petrov YuA, Blesmanovich AE. Ovarian hyperstimulation syndrome in the realities of our time. Health & Education millennium. Series Medicine. 2018; 20(4): 22-26. Russia (Алехина А.Г., Петров Ю.А., Блесманович А.Е. Синдром гиперстимуляции яичников в реалиях нашего времени //Здоровье и образование в XXI веке. 2018. Т. 20, № 4. С. 22-26)
Dobrokhotova YuE, Borovkova EI. Ovarian hyperstimulation: modern tactics of managing patients. Gynecology. 2017; 19(2): 19-22. Russia (Доброхотова Ю.Э., Боровкова Е.И. Гиперстимуляция яичников: современная тактика ведения пациенток //Гинекология. 2017. Т. 19, № 2. С. 19-22)
Petrov YuA, Alekhina AG, Blesmanovich AE. Ovarian hyperstimulation syndrome in the program of the extracorporal fertilization. Chief physician of the South of Russia. 2019; 2(66): 41-44. Russia (Петров Ю.А., Алехина А.Г., Блесманович А.Е. Синдром гиперстимуляции яичников в программе экстракорпорального оплодотворения //Главный врач Юга России. 2019. № 2(66). С. 41-44)
Strelchenko DA. Prediction of the development and features of the clinical course of ovarian hyperstimulation syndrome in the in vitro fertilization program based on the study of molecular genetic markers: authoref. dis. ... cand. med. sciences. M., 2017. 25 p. Russia (Стрельченко Д.А. Прогнозирование развития и особенностей клинического течения синдрома гиперстимуляции яичников в программе экстракорпорального оплодотворения на основании изучения молекулярногенетических маркеров: автореф. дис. … канд. мед. наук. М., 2017. 25 с.)
Scherbakova LN, Ivanova NV, Bugerenko AE, Panina OB. THE PREVENTION OF Development of syndrome of hyperstimulation of ovary in program of extra-corporeal fertilization. Medical Journal of the Russian Federation. 2015; 21(1): 28-31. Russia (Щербакова Л.Н., Иванова Н.В., Бугеренко А.Е., Панина О.Б. Предупреждение развития синдрома гиперстимуляции яичников в программе экстракорпорального оплодотворения //Российский медицинский журнал. 2015. Т. 21, № 1. С. 28-31)
Fiedler K, Ezcurra D. Predicting and preventing ovarian hyperstimulation syndrome (OHSS): the need for individualized not standardized treatment. Reprod Biol Endocrinol. 2012; 10: 32