PHEOCHROMOCYTOMA PRESENTING WITH CATECHOLAMINE CRISIS IN MEN 2A SYNDROME (RET MUTATION c.1900T>C) DURING PREGNANCY: A CLINICAL CASE
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Abstract
Pheochromocytoma manifesting during pregnancy or the early postpartum period is a rare but potentially fatal condition. Its diagnosis is challenging due to a nonspecific clinical presentation (paroxysmal arterial hypertension, tachycardia, catecholamine crisis) that often mimics preeclampsia, postpartum sepsis, myocarditis, or pericarditis. The combination of bilateral adrenal involvement and a young patient age necessitates a high index of suspicion for multiple endocrine neoplasia (MEN) syndromes.
This case report highlights the need to include pheochromocytoma in the differential diagnosis of hypertensive crises and tachycardia during pregnancy and the postpartum period. It also underscores the importance of a multidisciplinary approach, staged surgical management, and genetic screening for MEN syndromes in young patients presenting with bilateral adrenal involvement.
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