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Vadim Gelievich Moses
Elena Valentinovna Grishkevich
Elena Nikolaevna Orlova
Alena Vasilievna Ivannikova
Polina Andreevna Ovcharova
Elena Vladimirovna Rudaeva
Svetlana Ivanovna Elgina
Kira Borisovna Moses

Abstract

Eclampsia is a rare but potentially fatal complication of pregnancy, childbirth, and the postpartum period. The risk of developing it is significantly higher in multiple pregnancies. The initial seizure often occurs during or after delivery frequently against a background of blood pressure readings that appear satisfactory which complicates prediction and necessitates a high level of clinical vigilance.
The case report presented here illustrates the unpredictable onset of eclampsia in the early postpartum period despite relatively stable blood pressure readings prior to delivery; it highlights the need for neuroimaging to confirm posterior reversible encephalopathy syndrome (PRES), the importance of timely differential diagnosis regarding thrombotic microangiopathies, and the value of a multidisciplinary approach, including the use of telemedicine, in managing patients with severe obstetric complications.
We describe the case of a 20-year-old patient whose early postoperative period was complicated by atonic uterine hemorrhage; several hours later, she experienced her first generalized tonic-clonic seizure, followed by the development of multiorgan failure (involving the cardiovascular, cerebral, hepatic, and renal systems, as well as pancytopenia). Brain MRI revealed multiple cortical-subcortical lesions in the frontal, parietal, and occipital lobes, consistent with posterior reversible encephalopathy syndrome. Complete neurological, hematological, and hepatic recovery was achieved through the administration of magnesium sulfate, antihypertensive and antibacterial agents, and replacement therapy.

Keywords

eclampsia, postpartum period, multiple pregnancy, posterior reversible encephalopathy syndrome, postpartum hemorrhage, thrombotic microangiopathy

Author Biographies

Vadim Gelievich Moses,

doctor of medical sciences, professor, director of the Medical Institute

Elena Valentinovna Grishkevich,

head of the department of pregnancy pathology

Elena Nikolaevna Orlova,

physician-therapist of the obstetrics department of pregnancy pathology

Alena Vasilievna Ivannikova,

obstetrician-gynecologist of the obstetrics department of pregnancy pathology

Polina Andreevna Ovcharova,

obstetrician‑gynecologist at the department of obstetric pathology of pregnancy

Elena Vladimirovna Rudaeva,

candidate of medical sciences, docent, docent of the department of obstetrics and gynecology named after G.A. Ushakova

Svetlana Ivanovna Elgina,

doctor of medical sciences, docent, professor of the department of obstetrics and gynecology named after G.A. Ushakova

Kira Borisovna Moses,

assistant of the department of polyclinic therapy and nursing

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.

How to Cite

Moses, V. G., Grishkevich, E. V., Orlova, E. N., Ivannikova, A. V., Ovcharova, P. A., Rudaeva, E. V., Elgina, S. I., & Moses, K. B. (2026). ECLAMPSIA AND POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME IN THE EARLY POSTPARTUM PERIOD AFTER PRETERM TWIN DELIVERY: A CASE REPORT. Mother and Baby in Kuzbass, 4. https://mednauki.ru/index.php/MD/article/view/1586

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