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Elena Vladimirovna Rudaeva
Elena Valentinovna Grishkevich
Alena Vasilievna Ivannikova
Svetlana Ivanovna Elgina
Kira Borisovna Moses
Vadim Gelievich Moses
Elena Germanovna Rudaeva

Abstract

Multiple congenital malformations (CMF) represent one of the most challenging problems in modern perinatology and neonatology. Their timely diagnosis, prognosis, and family counseling require an interdisciplinary approach. This clinical case illustrates a severe variant of CMF with predominant involvement of the musculoskeletal system (MSS) and the respiratory system, which ultimately led to an unfavorable perinatal outcome.

Keywords

multiple fetal malformations, ultrasound diagnostics, perinatal outcome, prenatal diagnostics

Author Biographies

Elena Vladimirovna Rudaeva,

candidate of medical sciences, docent, docent of the department of obstetrics and gynecology named after G.A. Ushakova

Elena Valentinovna Grishkevich,

head of the obstetrics department of pregnancy pathology

Alena Vasilievna Ivannikova,

obstetrician-gynecologist of the obstetrics department of pregnancy pathology

Svetlana Ivanovna Elgina,

doctor of medical sciences, docent, professor of the department of obstetrics and gynecology named after G.A. Ushakova

Kira Borisovna Moses,

assistant of the department of polyclinic therapy and nursing

Vadim Gelievich Moses,

doctor of medical sciences, professor, director of the Medical Institute

Elena Germanovna Rudaeva,

candidate of medical sciences, docent, docent of the department of childhood diseases

Article Details

Information about financing and conflict of interests

The study had no sponsorship.
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.

How to Cite

Rudaeva, E. V., Grishkevich, E. V., Ivannikova, A. V., Elgina, S. I., Moses, K. B., Moses, V. G., & Rudaeva, E. G. (2026). MULTIPLE FETAL MALTFORMATIONS (CLINICAL CASE). Mother and Baby in Kuzbass, 27(1). https://mednauki.ru/index.php/MD/article/view/1413

References

1. Nechunaeva AN, Botoeva EA, Zhovtun LM. Analysis of the frequency of detection of congenital malformations in the fetus over the past 3 years. Vestnik Buryatskogo gosudarstvennogo universiteta. Medicina i farmaciya. 2020; 1: 75-82. Russian (Нечунаева А.Н., Ботоева Е.А., Жовтун Л.М. Анализ частоты выявления врожденных пороков развития у плода за последние 3 года //Вестник Бурятского государственного университета. Медицина и фармация. 2020. Т. 1. С. 75-82.) doi: 10.18101/2306-1995-2020-1-75-82

2. Padmakumar N, Khan HS. A foetus with cystic fibrosis – To treat or not to treat? Respir Med Res. 2023; 83: 101006. doi: 10.1016/j.resmer.2023.101006

3. Guseva M, Shirokova N, Kapitonova O, Gnetetskaya V, Blagodatskikh K, Tarasova J, et al. Application of Whole-Exome Sequencing (WES) for Prenatal Determination of Causes of Fetal Abnormalities. Genes (Basel). 2025; 16(5): 547. doi: 10.3390/genes16050547

4. Li D, Donnelley M, Parsons D, Habgood MD, Schneider-Futschik EK. Extent of foetal exposure to maternal elexacaftor/tezacaftor/ivacaftor during pregnancy. Br J Pharmacol. 2024; 181(15): 2413-2428. doi: 10.1111/bph.16417

5. Gabler E, Nissen M, Altstidl TR, Titzmann A, Packhauser K, Maier A, et al. Fetal Re-Identification in Multiple Pregnancy Ultrasound Images Using Deep Learning. Annu Int Conf IEEE Eng Med Biol Soc. 2023; 2023: 1-4. doi: 10.1109/EMBC40787.2023.10340336

6. Mulcahy C, McAuliffe FM. Routine Doppler ultrasound in twin pregnancy. Best Pract Res Clin Obstet Gynaecol. 2022; 84: 43-54. doi: 10.1016/j.bpobgyn.2022.08.002

7. Ushakov F, Sacco A, Pandya P. First-trimester 3D fetal neurosonography: five standardised views. J Obstet Gynaecol. 2024; 44(1): 2361848. doi: 10.1080/01443615.2024.2361848

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