ГОРМОНОПОДОБНЫЕ КСЕНОБИОТИКИ И ГИНЕКОЛОГИЧЕСКИЕ ПРОБЛЕМЫ


Червов В.О., Артымук Н.В., Данилова Л.Н.

Аннотация


В обзоре проведен анализ публикаций, обнаруженных в результате поиска в информационных базах систем: PubMed, Cochrane, Medscape, Medline, femb, e-library, Российская государственная библиотека (РГБ), посвященных вопросу роли ксенобиотиков в гинекологической патологии. Полученные результаты свидетельствуют о том, что ряд веществ, относящихся к гормоноподобным ксенобиотикам, негативно влияют на репродуктивное здоровье женщин, беременность и исходы родов, увеличивают риск возникновения онкологических заболеваний органов малого таза и молочных желез.


Ключевые слова


ксенобиотики; бесплодие; рак молочной железы; рак эндометрия; преждевременная овариальная недостаточность; репродуктивная система

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Литература


Agency for Toxic Substances and Disease Registry (ATSDR) [Accessed May 1, 2015]; Toxicological Profile for Phenol. 2008. Available from: http://www.atsdr.cdc.gov/ToxProfiles/tp115.pdf

Birnbaum LS. The mechanism of dioxin toxicity: relationship to risk assessment. Environ Health Perspect. 1994; 102: 157-167

Błędzka D, Gromadzińska J, Wąsowicz W. Parabens. From environmental studies to human health. Environ Int. 2014; 67: 27-42

Bodwell JE, Kingsley LA, Hamilton JW. Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain. Chem Res Toxicol. 2004; 17: 1064-1076

Buck Louis GM, Peterson CM, Chen Z et al. Bisphenol A and phthalates and endometriosis: the Endometriosis: Natural History, Diagnosis and Outcomes Study. Fertil Steril. 2013; 100: 162-169

Bulzomi P, Marino M. Environmental endocrine disruptors: Does a sex-related susceptibility exist? Front Biosci (Landmark Ed). 2011; 16: 2478-2498

Caserta D, Bordi G, Ciardo F et al. The influence of endocrine disruptors in a selected population of infertile women. Gynecol Endocrinol. 2013; 29: 444-447

Caserta D, Maranghi L, Mantovani A, Marci R, Maranghi F, Moscarini M. Impact of endocrine disruptor chemicals in gynaecology. Human Reproduction Update. 2008; 14(1): 59-72

Chen HS, Chiang PH, Wang YC et al. Benzyl butyl phthalate induces necrosis by AhR mediation of CYP1B1 expression in human granulosa cells. Reprod Toxicol. 2012; 33: 67-75

Cooney MA, Buck Louis GM, Hediger ML, Vexler A, Kostyniak PJ. Organochlorine pesticides and endometriosis. Reprod Toxicol. 2010; 30: 365-369

Delclos KB, Camacho L, Lewis SM et al. Toxicity evaluation of bisphenol A administered by gavage to Sprague Dawley rats from gestation day 6 through postnatal day 90. Toxicol Sci. 2014; 139: 174-197

Desaulniers D, Leingartner K, Russo J et al. Modulatory effects of neonatal exposure to TCDD, or a mixture of PCBs, p,p'-DDT, and p-p'-DDE, on methylnitrosourea-induced mammary tumor development in the rat. Environ Health Perspect. 2001; 109: 739-747

Elizarova NN, Artymuk NV, Polenok EG. Immunological features of women with premature rupture of membranes in 22+0–36+6 weeks of pregnancy. Fundamental and Clinical Medicine. 2017; 2(3): 58-62. Russian (Елизарова Н.Н., Артымук Н.В., Поленок Е.Г. Иммунологические особенности женщин с преждевременным разрывом плодных оболочек в 22+0–36+6 недель беременности //Фундаментальная и клиническая медицина. 2017. Т. 2, № 3. С. 58-62)

Ewa B, Danuta M-Š. Polycyclic aromatic hydrocarbons and PAH-related DNA adducts. Journal of Applied Genetics. 2017; 58(3): 321-330

Ferguson KK, McElrath TF, Meeker JD. Environmental phthalate exposure and preterm birth. JAMA Pediatr. 2014; 168: 61-67

Gore AC, Chappell VA, Fenton SE et al. EDC-2: The Endocrine Society’s Second Scientific Statement on Endocrine-Disrupting Chemicals. Endocrine Reviews. 2015; 36(6): E1-E150

Grindler NM, Allsworth JE, Macones GA, Kannan K, Roehl KA, Cooper AR. Persistent organic pollutants and early menopause in U.S. women. PLoSOne. 2015; 10: e0116057

Gupta RK, Singh JM, Leslie TC, Meachum S, Flaws JA, Yao HH. Di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate inhibit growth and reduce estradiol levels of antral follicles in vitro. Toxicol Appl Pharmacol. 2010; 242: 224-230

Hauser R, Calafat AM. Phthalates and human health. Occup Environ Med. 2005; 62(11): 806-818

Hiroi H, Tsutsumi O, Takeuchi T et al. Differences in serum bisphenol A concentrations in premenopausal normal women and women with endometrial hyperplasia. Endocr J. 2004; 51: 595-600

Johnson PI, Sutton P, Atchley DS et al. The Navigation Guide-evidence-based medicine meets environmental health: systematic review of human evidence for PFOA effects on fetal growth. Environ Health Perspect. 2014; 122: 1028-1039

Kadhel P, Monfort C, Costet N et al. Chlordecone exposure, length of gestation, and risk of preterm birth. Am J Epidemiol. 2014; 179: 536-544

Kawaguchi H, Miyoshi N, Miyamoto Y et al. Effects of fetal exposure to diethylstilbestrol on mammary tumorigenesis in rats. J Vet Med Sci. 2009; 71: 1599-1608

Kazantseva EV. Influence of anthropogenic chemicals on the course of pregnancy. Obstetrics and gynecology. 2013; 2: 18-23. Russian (Казанцева Е.В. Влияние антропогенных химических веществ на течение беременности //Акушерство и гинекология. 2013. № 2. С. 18-23)

Kogevinas M, Becher H, Benn T et al. Cancer mortality in workers exposed to phenoxyherbicides, chlorophenols, and dioxins. An expanded and updated international cohort study. Am J Epidemiol. 1997; 145: 1061-1075

Krasilnikova KS, Polenok EG, Anosova TP, Anosov MP, Gordeeva LA, Glushkova OA. Association of the immune response to xeno- and endobiotics and polymorphism of the genes of enzymes of their biotransformation with the onset of congenital malformations of the fetus. Acta Biomedica Scientifica. 2012; 3-2(85): 96-99. Russian (Красильникова К.С., Поленок Е.Г., Аносова Т.П., Аносов М.П., Гордеева Л.А., Глушкова О.А. и др. Ассоциация иммунного ответа на ксено- и эндобиотики и полиморфизма генов ферментов их биотрансформации с возникновением врожденных пороков развития плода //Acta Biomedica Scientifica. 2012. № 3-2(85). С. 96-99)

López-Carrillo L, Hernández-Ramírez RU, Calafat AM et al. Exposure to phthalates and breast cancer risk in northern Mexico. Environ Health Perspect. 2010; 118: 539-544

Mahalingaiah S, Missmer SA, Maity A et al. Association of hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) with in vitro fertilization (IVF) outcomes. Environ Health Perspect. 2012; 120: 316-320

Martínez-Zamora MA, Mattioli L, Parera J et al. Increased levels of dioxin-like substances in adipose tissue in patients with deep infiltrating endometriosis. Hum Reprod. 2015; 30: 1059-1068

Matsui K, Nishii S, Oka M. P450 aromatase inhibition assay using a competitive ELISA. J Pharm Biomed Anal. 2005; 38; 307-312

Migeot V, Albouy-Llaty M, Carles C et al. Drinking-water exposure to a mixture of nitrate and low-dose atrazine metabolites and small-for-gestational age (SGA) babies: a historic cohort study. Environ Res. 2013; 122: 58-64

Mustafa MD, Banerjee BD, Ahmed RS, Tripathi AK, Guleria K. Gene-environment interaction in preterm delivery with special reference to organochlorine pesticides. Mol Hum Reprod. 2013; 19: 35-42

Naidoo S, London L, Burdorf A, Naidoo R, Kromhout H. Spontaneous miscarriages and infant deaths among female farmers in rural South Africa. Scand J Work Environ Health. 2011; 37: 227-236

OECD. [Accessed May 1, 2015];OECD Environmental Outlook to 2030. 2008 Available from: http://www.keepeek.com/Digital-Asset-Management/oecd/environment/oecd-environmental-outlook-to-2030_9789264040519-en#page1

Petro EM, Leroy JL, Covaci A et al. Endocrine-disrupting chemicals in human follicular fluid impair in vitro oocyte developmental competence. Hum Reprod. 2012; 27: 1025-1033

Reinsberg J, Wegener-Toper P, van der Ven K, van der Ven H, Klingmueller D. Effect of mono-(2-ethylhexyl) phthalate on steroid production of human granulosa cells. Toxicol Appl Pharmacol. 2009; 239: 116-123

Revich B, Aksel E, Ushakova T et al. Dioxin exposure and public health in Chapaevsk, Russia. Chemosphere. 2001; 43: 951-966

Rissman EF, Adli M. Minireview: transgenerational epigenetic inheritance: focus on endocrine disrupting compounds. Endocrinology. 2014; 155: 2770-2780

Sathyanarayana S, Basso O, Karr CJ et al. Maternal pesticide use and birth weight in the Agricultural Health Study. J Agromedicine. 2010; 15: 127-136

Smith KW, Souter I, Dimitriadis I et al. Urinary paraben concentrations and ovarian aging among women from a fertility center. Environ Health Perspect. 2013; 121: 1299-1305

Snijder CA, teVelde E, Roeleveld N, Burdorf A. Occupational exposure to chemical substances and time to pregnancy: a systematic review. Hum Reprod Update. 2012; 18: 284-300

Souter I, Smith KW, Dimitriadis I et al. The association of bisphenol-A urinary concentrations with antral follicle counts and other measures of ovarian reserve in women undergoing infertility treatments. Reprod Toxicol. 2013; 42: 224-231

Suhih GT, Adamyan LV. Reproductive health care is an important part of healthcare modernization. In: Problems of reproduction. Special issue: materials of the 6th International Congress on Reproductive Medicine, January 17-20, 2012, Moscow. M.: MediaSphere; 2012. S. 5-10. Russian (Сухих Г.Т., Адамян Л.В. Охрана репродуктивного здоровья – важный раздел модернизации здравоохранения. В сб.: Проблемы репродукции. Специальный выпуск: матер. VI Междунар. конгресса по репрод. медицине, 17-20 января 2012, Москва. М.: МедиаСфера; 2012. С. 5-10)

Toft G, Thulstrup AM, Jönsson BA et al. Fetal loss and maternal serum levels of 2,2′,4,4′,5,5′-hexachlorbiphenyl (CB-153) and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE) exposure: a cohort study in Greenland and two European populations. Environ Health. 2010; 9: 22

Vabre P, Gatimel N, Moreau J et al. Environmental pollutants, a possible etiology for premature ovarian insufficiency: a narrative review of animal and human data. Environmental Health. 2017; 16: 37

Vieira VM, Hoffman K, Shin HM, Weinberg JM, Webster TF, Fletcher T. Perfluorooctanoic acid exposure and cancer outcomes in a contaminated community: a geographic analysis. Environ Health Perspect. 2013; 121: 318-323

Wang Y, Yu J, Luo X et al. Abnormal regulation of chemokine TECK and its receptor CCR9 in the endometriotic milieu is involved in pathogenesis of endometriosis by way of enhancing invasiveness of endometrial stromal cells. Cell Mol Immunol. 2010; 7: 51-60

Xu C, Chen JA, Qiu Z et al. Ovotoxicity and PPAR-mediated aromatase downregulation in female Sprague-Dawley rats following combined oral exposure to benzo[a]pyrene and di-(2-ethylhexyl) phthalate. Toxicol Lett. 2010; 199: 323-332

Ziv-Gal A, Craig ZR, Wang W, Flaws JA. Bisphenol A inhibits cultured mouse ovarian follicle growth partially via the aryl hydrocarbon receptor signaling pathway. Reprod Toxicol. 2013; 42: 58-67


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