Main Article Content
Abstract
Alveococcus (alveolar echinococcosis, multichamber echinococcosis) is helminthiasis from the group of cestodosis. Alveococcus has some syndromes, such as heavy chronic process, primary tumor of the liver for which is characteristic infiltrative parasitic tissue growth, sometimes with metastases to the brain and lungs as well as to other organs. This disease is always lethal. The probability of survival after 10 years is only 10-20 % without therapy. The surgery with removal of the parasitic tumor is method of patient choice and the only radical solution for the treatment. A chemotherapy with antihelmintic drugs is efficient only in some cases.
Goal: is to present clinical case of progressing alveococcus, what was caused by the long-term active immunosuppressive therapy after liver transplantation. This one leads to growth of parasites and the ineffectiveness of antiparasitic treatment with albendazole.
Results. In the article the case of spread alveolar liver echinococcosis Р4, Nx, Mx is described, the state is after liver transplantation (1994). The condition is after a lot of surgeries of removal of metastatic parasitic nodes in the retroperitoneal space, spine, anterior thoracic and abdominal wall (1996-2009), complicated by multiple metastases of alveococcus in the lungs, brain, gates of the liver and retroperitoneal space, deep vein thrombosis of the lower extremities.
Application. Gastroenterology.
Keywords
Article Details
Information about financing and conflict of interests
The authors declare that they have no apparent or potential conflicts of interest related to the publication of this article.
This work is licensed under a Creative Commons Attribution 4.0 License.
How to Cite
References
Torgerson PR, Keller K, Magnotta M, Ragland N. The global burden of alveolar echinococcosis. PLoS Negl Trop Dis. 2010; 4(6): e722. doi: 10.1371/journal.pntd.0000722
Pyshkin SA, Borisov DL, Maslov VG. Surgical treatment of liver alveococcosis. Actual problems of surgical hepatology: Materials of the XIX international congress of surgeons-hepatologists of Russia and CIS countries. Irkutsk, 2012. P. 95. Russian (Пышкин С.А., Борисов Д.Л., Маслов В.Г. Хирургическое лечение альвеококкоза печени //Актуальные проблемы хирургической гепатологии: Сб. матер. XIX междунар. конгр. хирургов-гепатологов России и стран СНГ. Иркутск, 2012. С. 95)
Spicher M, Roethlisberger C, Lany C, Stadelmann B, Keiser J, Ortega-Mora LM et al. In vitro and in vivo treatments of echinococcus protoscoleces and metacestodes with artemisinin and artemisinin derivatives. Antimicrob Agents Chemother. 2008; 52(9): 3447-50. doi: 10.1128/AAC.00553-08
Skipenko OG, Shatverian GA, Bagmet NN, Chekunov DA, Bedzhanian AL, Ratnikova NP, Zavoĭkin VD. Alveococcosis of liver: retrospective analysis of treatment of 51 patients. Pirogov Russian Journal of Surgery. 2012; 12: 4-13. Russian (Скипенко О.Г., Шатверян Г.А., Багмет Н.Н., Чекунов Д.А., Беджанян А.Л., Ратникова Н.П., Завойкин В.Д. Альвеококкоз печени: ретроспективный анализ лечения 51 больного //Хирургия. Журнал им. Н.И. Пирогова. 2012. № 12. С. 4-13)
Shaw AK, Gambhir RP, Chaudhry R, Jaiswal SS. Ecchinococcus multilocularis causing alveolar hydatid disease liver: a rare occurrence in Indian subcontinent. Trop Gastroenterol. 2010; 31(2): 119-120