НЕКОТОРЫЕ АСПЕКТЫ ЭТИОПАТОГЕНЕЗА И ДИАГНОСТИКИ НЕКРОТИЗИРУЮЩЕГО ЭНТЕРОКОЛИТА У ДЕТЕЙ


Ким Л.В., Желев В.А., Слизовский Г.В., Девальд Э.В., Голикова Е.В., Солнышко А.Л., Ермоленко С.П., Рейм А.С.

Аннотация


Несмотря на то, что о некротизирующем энтероколите (НЭК) известно вот уже около двух веков, а интенсивное изучение заболевания продолжается в течение последних 50 лет, НЭК остается нерешенной проблемой. В связи с появлением новых возможностей и технологий выхаживания недоношенных детей, интерес к исследованиям возрос, число публикаций по НЭК увеличивалось с 1-2 в год в начале 70-х годов прошлого столетия до более 400 в 2020 году. Многие исследователи посвятили всю свою карьеру вопросам понимания, профилактики и лечения НЭК. Однако, уровень летальности остается практически неизменным последние три десятилетия. Настоящий обзор представляет собой описание известных на сегодняшний день факторов риска, аспектов диагностики и патогенеза заболевания.


Ключевые слова


некротизирующий энтероколит; недоношенный; новорожденный; диагностика

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Литература


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