Основное содержимое статьи

Тамара Михайловна Шукевич
Татьяна Евгеньевна Помыткина
Кира Борисовна Мозес
Вадим Гельевич Мозес
Елена Владимировна Рудаева
Светлана Ивановна Елгина
Игорь Сергеевич Захаров
Мария Николаевна Сурина

Аннотация

Цель исследования – провести аналитический обзор современных источников научной литературы, освещающих вопросы патогенеза алкогольной болезни печени.

Материалы и методы. Проведен анализ 55 отечественных и зарубежных источников литературы по данной теме.

Результаты. По результатам анализа научных данных обновлено представление о патогенезе алкогольной болезни печени.

Заключение. Алкогольная болезнь печени ассоциирована с ближайшими и отдаленными фатальными рисками, что делает ее актуальной проблемой. Проведенный анализ свидетельствует, что данная патология требует дальнейшего изучения.

Ключевые слова

алкогольная болезнь печени, алкогольный цирроз, алкогольный стеатоз, алкогольный стеатогепатит

Сведения об авторах

Тамара Михайловна Шукевич,
зав. отделением гастроэнтерологии
Татьяна Евгеньевна Помыткина,
доктор мед. наук, зав. кафедрой поликлинической терапии и сестринского дела
Кира Борисовна Мозес,
ассистент, кафедра поликлинической терапии и сестринского дела
Вадим Гельевич Мозес,
доктор мед. наук, профессор, зав. кафедрой акушерства и гинекологии № 1
Елена Владимировна Рудаева,
канд. мед. наук, доцент, кафедра акушерства и гинекологии им. Г.А. Ушаковой
Светлана Ивановна Елгина,
доктор мед. наук, профессор кафедры акушерства и гинекологии им. Г.А. Ушаковой
Игорь Сергеевич Захаров,
доктор мед. наук, доцент, профессор кафедры акушерства и гинекологии им. Г.А. Ушаковой
Мария Николаевна Сурина,
канд. мед. наук, доцент, кафедра акушерства и гинекологии им. Г.А. Ушаковой

Информация о статье

Информация о финансировании и конфликте интересов

Работа выполнена без использования внешних источников финансирования.
Авторы заявляют об отсутствии явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.

Как цитировать

Шукевич, Т. М., Помыткина, Т. Е., Мозес, К. Б., Мозес, В. Г., Рудаева, Е. В., Елгина, С. И., Захаров, И. С., & Сурина, М. Н. (2020). АЛКОГОЛЬНАЯ БОЛЕЗНЬ ПЕЧЕНИ – КЛЮЧЕВЫЕ ВОПРОСЫ ЭПИДЕМИОЛОГИИ И ПАТОГЕНЕЗА ЗАБОЛЕВАНИЯ. Медицина в Кузбассе, 19(1), 5-10. https://doi.org/10.24411/2687-0053-2020-10002

Список литературы

Mathurin P, Hadengue A, Bataller R. EASL Clinical Practical Guidelines: Management of Alcoholic Liver Disease. European Association for the Study of the Liver. J of Hepatology. 2012; 57: 399-420

Jürgen Rehm. The risks associated with alcohol use and alcoholism. Alcohol Res Health. 2011; 34(2): 135-143

Mokdad AA, Lopez AD, Shahraz S, et al. Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis. BMC Med. 2014; 12: 145

Sheron N. Alcohol and liver disease in Europe: simple measures have the potential to prevent tens of thousands of premature deaths. J Hepatol. 2016; 64: 957-967

Axley PD, Richardson CT, Singal AK. Epidemiology of Alcohol Consumption and Societal Burden of Alcoholism and Alcoholic Liver Disease. Clin Liver Dis. 2019; 23(1): 39-50

Bosetti C, Levi F, Lucchini F, Zatonski WA, Negri E, et al. Worldwide mortality from cirrhosis: an update to 2002. J Hepatol. 2017; 46: 827-839

Rehm J, Room R, Graham K, et al. The relationship of average volume of alcohol consumption and patterns of drinking to burden of disease: An overview. Addiction. 2003; 98(9): 1209-1228

Mackenbach JP, Kulhánová I, Bopp M, Borrell C, Deboosere P, Kovács K et al. Inequalities in Alcohol-Related Mortality in 17 European Countries: A Retrospective Analysis of Mortality Registers. PLoS Med. 2015; 12(12): e1001909

Indicator Code Book Global Information System on Alcohol and Health. WHO, 2016

Russian statistical yearbook. 2019: Statsb./Rosstat. P76 M., 2019; 708 p. Russian (Российский статистический ежегодник. 2019: Стат.сб./Росстат. Р76 М., 2019. 708 с.)

Stickel F, Datz C, Hampe J, Bataller R. Erratum: Pathophysiology and Management of Alcoholic Liver Disease: Update 2016. Gut Liver. 2017; 11(3): 447

2015-2020 Dietary Guidelines for Americans. In: 8th ed. U.S. Department of Health and Human Services and U.S. Department of Agriculture; 2015

WHO. Food based dietary guidelines. 2003

Patra J, Taylor B, Rehm J. Deaths associated with high-volume drinking of alcohol among adults in Canada in 2002: A need for primary care intervention? Contemporary Drug Problems. 2009; 36(2): 283-301

Shield KDR, Rehm, J. Public health successes and missed opportunities Trends in alcohol consumption and attributable mortality in the WHO European Region, 1990–2014. In. WHO. Copenhagen, Denmark: WHO Regional Office for Europe; 2016

Becker U, Grønbaek M, Johansen D, et al. Lower risk for alcohol-induced cirrhosis in wine drinkers. Hepatology. 2002; 35: 868-875

Kennedy OJ, Roderick P, Buchanan R, et al. Systematic review with meta-analysis: coffee consumption and the risk of cirrhosis. Aliment Pharmacol Ther. 2016; 43: 562-574

Dam MK, Flensborg-Madsen T, Eliasen M et al. Smoking and risk of liver cirrhosis: a population-based cohort study. Scand J Gastroenterol. 2013; 48: 585-591

Shoreibah M, Anand BS, Singal AK. Alcoholic hepatitis and concomitant hepatitis C virus infection. World J Gastroenterol. 2014; 20: 11929-11934

Hart CL, Morrison DS, Batty GD, et al. Effect of body mass index and alcohol consumption on liver disease: analysis of data from two prospective cohort studies. BMJ. 2010; 340: c1240

Reed T, Page WF, Viken RJ, et al. Genetic predisposition to organ-specific endpoints of alcoholism. Alcohol Clin Exp Res. 1996; 20: 1528-1533

Eagon PK. Alcoholic liver injury: influence of gender and hormones. World J Gastroenterol. 2010; 16: 1377-1384

Baraona E, Abittan CS, Dohmen K, et al. Gender differences in pharmacokinetics of alcohol. Alcohol Clin Exp Res. 2001; 25: 502-507

Moses VG. Hormonal contraception in women at risk for the development of arterial and venous thrombosis. Questions of gynecology, obstetrics and perinatology. 2009; 2: 83-87. Russian (Мозес В.Г. Гормональная контрацепция у женщин группы риска по развитию артериальных и венозных тромбозов //Вопросы гинекологии, акушерства и перинатологии. 2009. Т. 8, № 2. С. 83-87)

Prince M, Chetwynd A, Newman W, et al. Survival and symptom progression in a geographically based cohort of patients with primary biliary cirrhosis: follow-up for up to 28 years. Gastroenterology. 2002; 123(4): 1044-1051

Buch S, Stickel F, Trépo E, et al. A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. Nat Genet. 2015; 47: 1443-1448

Stickel F, Moreno C, Hampe J, Morgan MY. The genetics of alcohol dependence and alcohol-related liver disease. J Hepatol. 2017; 66: 195-211

Rocco A, Compare D, Angrisani D. et al. Alcoholic disease: liver and beyond. World J Gastroenterol. 2014; 20(40): 14652-14659

Teschke R. Microsomal ethanol-oxidizing system (MEOS): Success over 50 years and an encouraging future. Alcohol Clin. Exp. Res. 2019; 43: 386-400

Teschke R., Zhu Y. Opinion: Intestinal microbiome, endotoxins, cytochrome P450 2E1, and the gut-liver axis in alcoholic liver disease. EC Gastroenterology Dig. Syst. 2019; 6: 66-75

Salaspuro M. Epidemiological aspects of alcohol and alcoholic liver disease, ethanol metabolism, and pathogenesis of alcoholic liver injury. Oxf. Textb. Clin. Hepatol. 1991; 2: 791-810

Pizon A.F., Becker C.E., Bikin D. The clinical variations in ethanol toxicokinetics. Toxicol Rev. 2007; 3: 63-72

Teschke R. Alcoholic steatohepatitis (ASH) and alcoholic hepatitis (AH): Cascade of events, clinical aspects, and pharmacotherapy options. Expert Opin. Pharm. 2018; 19: 779-793

Parker R., Kim SJ., Gao B. Alcohol, adipose tissue and liver disease: Mechanistic links and clinical considerations. Nat. Rev. Gastroenterol. Hepatol. 2018; 15: 50-59

Cederbaum AI. Alcohol metabolism. Clin. Liver Dis. 2012; 16: 667-685

Geschke R., Hasumura Y., Joly J.G., et al. Microsomal ethanol-oxidizing system (MEOS): Purification and properties of a rat liver system free of catalase and alcohol dehydrogenase. Biochem. Biophys. Res. Commun. 1972; 49: 1187-1193

Lieber CS., DeCarli LM. Reduced nicotinamide-adenine dinucleotide phosphate oxidase: Enhanced by ethanol consumption. Science. 1970; 170: 78-80

Waxman DJ, Holloway MG. Sex differences in the expression of hepatic drug metabolizing enzymes. Mol Pharmacol. 2009; 76(2): 215-228

Teschke R. Alcoholic Liver Disease: Current Mechanistic Aspects with Focus on Their Clinical Relevance. Biomedicines. 2019; 7(3): 68

Lieber C.S. Alcohol and the liver: 1994 update. Gastroenterology. 1994; 106: 1085-1105

Rehm J, Taylor B, Mohapatra S, et al. Alcohol as a risk factor for liver cirrhosis: a systematic review and meta-analysis. Drug Alcohol Rev. 2010; 29: 437-445

Osna NA, Donohue TM, Kharbanda KK. Alcoholic liver disease: Pathogenesis and current management. Alcohol Res. 2017; 38: 147-161

Neuman MG, French SW, Zakhari S, et al. Alcohol, microbiome, life style influence alcohol and non-alcoholic organ damage. Exp. Mol. Pathol. 2017; 102: 162-180

Lieber CS, DeCarli LM, Matsuzaki S, Ohnishi K, Teschke R. The microsomal ethanol oxidizing system (MEOS). Methods Enzym. 1978; 52: 355-367

Brunt EM, Neuschwander-Tetri BA, Burt AD. Fatty liver disease: alcoholic and non-alcoholic. In: Burt A, Portmann B, Ferrell L, editors. MacSween’s pathology of the liver. 6th ed. Edinburgh: Churchill Livingstone, 2012. P. 293-360

Roh YS, Zhang B, Loomba R, Seki E. TLR2 and TLR9 contribute to alcohol-mediated liver injury through induction of CXCL1 and neutrophil infiltration. Am J Physiol Gastrointest Liver Physiol. 2015; 309: 30-41

An L, Wang X, Cederbaum AI. Cytokines in alcoholic liver disease. Arch Toxicol. 2012; 86: 1337-1348

Petrasek J, Csak T, Szabo G. Toll-like receptors in liver disease. Adv Clin Chem. 2013; 59: 155-201

Dubuquoy L, Louvet A, Lassailly G, Truant S, Boleslawski E, Artru F, et al. Progenitor cell expansion and impaired hepatocyte regeneration in explanted livers from alcoholic hepatitis. Gut. 2015; 64: 1949-1960

Lanthier N, Rubbia-Brandt L, Lin-Marq N, et al. Hepatic cell proliferation plays a pivotal role in the prognosis of alcoholic hepatitis. J Hepatol. 2015; 63: 609-621

Sancho-Bru P, Altamirano J, Rodrigo-Torres D, et al. Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis. Hepatology. 2012; 55: 1931-1941

Schuppan D. Liver fibrosis: common mechanisms and antifibrotic therapies. Clin Res Hepatol Gastroenterol. 2015; 39: 51-59

Patsenker E, Stoll M, Millonig G, et al. Cannabinoid receptor type I modulates alcohol-induced liver fibrosis. Mol Med. 2011; 17: 1285-1294

Fattovich G, Stroffolini T, Zagni I, Donato F. Hepatocellular carcinoma in cirrhosis: incidence and risk factors. Gastroenterology. 2004; 127: 35-50

Villanueva A, Portela A, Sayols S, et al. DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma. Hepatology. 2015; 61: 1945-1956

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