EARLY DIAGNOSIS OF ACUTE KIDNEY INJURY IN CHILDREN WITH ACUTE INTESTINAL INFECTIONS COMPLICATED BY TOXICOSIS WITH EXSICOSIS
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Abstract
The purpose of the study – to characterize acute kidney injury (AKI) in children with acute intestinal infections (AKI complicated by toxicosis with exicosis (TE).
Materials and methods of research. The study included 135 children aged 2 months to 6 years with manifestations of AKI complicated by TE I and II grade (TE I, TE II). The stages of AKI were determined according to the KDIGO classification and the pRIFLE children's scale in children with impaired glomerular filtration rate.
The results of the study. Among children with AKI with TE I according to KDIGO stage 1 risk of AKI was identified in 6 (8%) patients. According to pRIFLE, stage 1 risk was identified in 17 (24%) patients and stage 2 damage in 20 (28%) patients, who were registered statistically significantly more often (p < 0.05).
Among children with AKI with TE II according to KDIGO stage 1 risk of AKI was registered in 13 (21%) children. According to pRIFLE, stage 1 risk was identified in 13 (21%) patients, stage 2 in 27 (43%) patients, stage 3 insufficiency in 4 (6%) patients. The stages of risk and injury were significantly more frequently recorded (p < 0.05).
Conclusion. According to the KDIGO classification, only stage 1 of AKI risk was recorded in children with AKI and TE. According to the pRIFLE scale, the stages of risk, damage and insufficiency were recorded among the identified stages of AKI, and risk and damage were statistically significantly more often recorded among children with AKI with TE I and TE II.
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